Kiko Kono, M.D.
Profile
Graduated from Kawasaki Medical School. Worked as a dermatologist for about 20 years at core hospitals. After many years of experience and achievements, he became a cosmetic dermatologist. His practice style is to examine the skin thoroughly and pursue what is happening where on the skin and approach the problem. Her specialties include customized treatment, laser treatment, Botox, and skin growth injections. In her private life, she is a mother of two children.
Both PDRN and PN are ingredients derived from salmon. In this article, we’ll introduce a treatment that’s perfect for those who want to maintain youthful-looking skin as they age. If you’ve ever wondered, “How effective is PDRN serum, really?” or “When do the effects of salmon injections start to show?”, be sure to check this out.
What Are PDRN and PN? Let’s Take a Look at Their Characteristics and Differences
PDRN (polydε-ribonucleotide) and PN (polynucleotide) are both ingredients derived from salmon.Expected to support skin cell regenerationCan be done.
PDRN and PN have structures very similar to human DNA, which makes them less likely to cause allergic reactions or side effects.It is expected to help promote collagen production and improve overall skin conditionI am sure you will.
Comparison Table of PDRN and PN
PDRN has a low-molecular-weight structure, andIt penetrates relatively quickly to every corner of the skinIt has several unique features. It helps moisturize the skin, improve elasticity, and reduce dullness to reveal a brighter complexion. At Yayoi Clinic, we use it as a Rejuran booster and as a preparatory treatment for Potenza and Dermapen procedures.
On the other hand, PN is a polymer, which means it is absorbed into the skin relatively slowly. Although the absorption rate is slow,One advantage is that the effects tend to last a long timeIt promotes skin regeneration, helping you achieve healthy, supple skin where wrinkles are less noticeable. At Yayoi Clinic, we use it as part of our “skin-nurturing” injections. We use Rejuran, Rejuran i, and Plural Densify for this treatment.
Features of PDRN | Rapid Penetration to Every Corner of the Skin
PDRN is a type of DNA fragment extracted from salmon sperm. Its main effects are as follows:
- For Youthful-Looking Skin
- Improve skin condition
- Anti-inflammatory effects
- Skin tone enhancement
Features of PN | Long-Lasting Effects
PN is a type of DNA fragment extracted from salmon testicles. When applied to the skin, it is expected to provide the following benefits.
- Increased skin elasticity
- Reduces sebum production
- Refine the texture
- Achieve firm, youthful-looking skin
Who Should Consider PDRN and PN?
If any of the following apply to you, we recommend PDRN or PN.
- I'm concerned about skin redness and inflammation
- I want to have clear, radiant skin
- I want to achieve a youthful-looking eye area
- I want to improve dullness and uneven skin tone
- I want to have naturally youthful skin
- My skin looks dull
- I want to improve my skin texture and skin conditions
However, all procedures carry some risk. We recommend starting by consulting with a cosmetic clinic.
For PDRN and PN, visit YAYOI CLINIC
Both PDRN and PN are salmon-derived ingredients, but they have different characteristics and effects. Learn about their characteristics and differences to find the method that best suits your needs.
Aesthetic Dermatology, Cosmetic Medicine, Cosmetic Surgery, Art Makeup in Hiroshima YAYOI CLINIC offers treatments for different skin, body, and facial concerns.
In order to offer a better option for everyone, we will assess each person's skin condition and formulate a treatment plan that meets their needs in terms of treatment duration, budget, and acceptable downtime.
If you have any concerns, please come for a counseling session first.
Description of treatment] Rejuran
Recommended frequency of treatment: 3 to 4 times every 2 to 3 weeks / once every 6 months as maintenance.
Cost】¥58,000〜¥204,000 ※Prices vary depending on the area and number of times.
Side effects/risks] Pain, redness, swelling, internal bleeding
Equipment used.
Rejuran treatments include procedures using unapproved drugs or medical devices in Japan.
The medicines and medical devices used for treatment were imported from Japan under the judgment of our doctors. Please refer to the following for information on medicines and other items of concern for personal importation.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
Serious risks, side effects, etc. may not have been identified.
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.
[Description of treatment] Potenza
Approximate number of treatments: 3 times every 4 to 6 weeks (every 2 weeks for melasma)
*The number of treatments varies depending on the treatment.
Cost] 1 time ¥54,780～¥104,500
Approximate duration of treatment: 3 to 5 months
Adverse effects/risks
Infection, hyperpigmentation, folliculitis, erythema
After the procedure, the pores may become blocked due to inflammation or swelling, and temporary acne may develop or worsen.
Depending on the treatment, bleeding may occur.
Swelling and redness may occur after the procedure.
Please note that effects may vary from person to person. Also, depending on the area to be treated, some patients may not achieve outstanding results.
Equipment used.
Treatment of potenza includes procedures using domestically unapproved drugs or medical devices.
The medicines and medical devices used for treatment were imported from Jeisys Medical Inc. under the judgment of our doctors. Please refer to the following for information on drugs and medical devices that should be imported by individuals.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
The following certifications have been obtained
-MFDS(2019.01)
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.
Description of treatment] Dermapen 4
Approximate number of treatments: Once every 2 to 4 weeks, or once every 6 to 8 weeks (1 course: 3 to 5 treatments)
*The treatment interval depends on the degree of bleeding.
Cost] 1 time ¥31,800～¥36,800
Adverse effects/risks
Redness and tingling may occur, but will generally subside within 1 to 2 days.
Symptoms such as peeling, internal bleeding, and swelling may appear for 7-10 days.
In rare cases, old keratin may peel off, but please be careful not to peel it off forcibly.
Equipment used.
Dermapen4 treatment involves the use of a domestically unapproved drug or medical device.
The drugs and medical equipment used for treatment were purchased from PRSS.Japan, Inc. under the judgment of our doctors.
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
The following certifications have been obtained
ISO 13485
CE Standard
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.
Description of treatment] Pull Real
Approximate number of treatments] Once every 2 to 3 weeks (1 course: about 3 treatments) *Treatment intervals vary depending on skin conditions.
Cost] ¥71,000 - ¥204,000 *Prices vary depending on the area and number of times.
[Side effects/risks] Post-treatment bleeding, edema, erythema without swelling, redness, swelling, itching, hematoma, tenderness, etc.
Equipment used.
Pluryal treatments include procedures using domestically unapproved drugs or medical devices.
The medicines and medical devices used for treatment were imported from MD Skin Solutions, Inc. under the judgment of our doctors.
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
-All products are CE certified in Europe.
About the Adverse Reactions Relief System for Drugs
-In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief Program.
