Dr. Yayoko Ito
Profile
Graduated from Hiroshima University School of Medicine. After working in the Department of General Medicine, he studied under doctors at the forefront of cosmetic medicine. After acquiring knowledge and skills in aesthetics, he became the director of YAYOI CLINIC in 2023. Her specialties include Botox, hyaluronic acid injections, and customized sagging treatment. His motto is to provide natural and pain-free treatments with careful consultation.
If you’re considering Rejuran (polynucleotide) injections in Hiroshima, you may be wondering, “How long will the results last?” or “Is there any downtime or pain?” In this article, we’ll explain in simple terms how Rejuran injections work, the results you can expect, and the downtime involved. We’ll also introduce the features of the treatment at YAYOI CLINIC in Hiroshima, as well as key points to keep in mind beforehand. If you’re interested in skin rejuvenation treatments or are considering Rejuran injections in Hiroshima, please use this article as a guide.
Frequently Asked Questions About Rejuran Injections
When considering cosmetic medical procedures, it’s important to make an informed decision after addressing any concerns or questions you may have. To begin with, we’ll explain some frequently asked questions about Rejuran injections and their answers.
■Q. When can I start wearing makeup after the treatment?
You can do so starting the next day (24 hours after the treatment)Please note: To protect your delicate skin immediately after the procedure, we ask that you refrain from wearing makeup on the day of your treatment. On the following day and beyond, if you notice any symptoms such as redness, swelling, or bruising, it is best to limit your makeup to the absolute minimum and avoid rubbing or irritating the treated area.
■Q. How long do the results last?
Although there are individual differences based on age, lifestyle, and other factors, in order to replenish the ingredients that help maintain a healthy skin foundation, changes willExpected to last for several monthsYes, it is possible. While you may notice a difference after just one treatment, continuing with regular treatments will help you maintain healthy skin for a longer period of time.
■Q. Will there be any change in the dark circles under my eyes?
Yes, depending on the type of dark circles, this is one of the treatments that can help make them less noticeable. Rejuran isSince this treatment promotes the skin's natural regeneration, it supports the production of collagen and elastin, among other things.It also provides firmness and elasticity to the eye area. This can help minimize the appearance of “blue circles”—caused by blood vessels showing through thin skin—and “dark circles”—caused by shadows formed as the skin loses firmness with age—potentially giving you a brighter-looking eye area.
What Is the Much-Talked-About “Rejuran Injection” Skin Rejuvenation Treatment? Expected Results and How It Works
Rejuran is one of the skin rejuvenation treatments currently gaining attention in the field of aesthetic medicine. Here, we’ll explain the expected results and how it works in an easy-to-understand way.
■ "Polynucleotide (PN)," the main ingredient in Rejuran, supports skin regeneration
The main ingredient in Rejuran injections, “polynucleotide (PN),” is derived from salmon DNA.Helps support the skin's natural repair process and improves the condition of skin damaged by aging and UV rays from within. In addition, thanks to its excellent skin-conditioning properties, it can help reduce redness and skin roughness, address age-related changes such as dryness and loss of firmness, and enhance the skin’s overall health. Rather than producing dramatic changes, it works gradually to improve the skin’s foundation, restoring natural firmness and elasticity to help achieve a youthful complexion.
■ Expected to help address fine lines, firmness, pores, and acne scars
Rejuran injections are designed to enhance the skin's overall ability to regenerate itself, soWe can address complex concernsBy supporting collagen production, your skin regains its elasticity, making fine lines and enlarged pores less noticeable. Unlike superficial treatments, this approach aims to give you plump, radiant skin from the inside out. Furthermore, by maintaining a healthy skin renewal cycle, it can address concerns such as uneven texture and unevenness caused by acne scars, helping to create a smoother complexion.
■Differences from Hyaluronic Acid Injections and Botox
While hyaluronic acid and Botox are temporary treatments that “fill in wrinkles” and “inhibit muscle movement,” Rejuran injections are a method that improves the skin’s condition by “supporting the skin’s natural regenerative ability.”
I've summarized the main differences in a table.
| treatment | feature | Concerns Where a Solution Is Likely |
| Rejuran Injections | Supports the skin's natural regenerative ability | Improved firmness and radiance, reduced fine lines, etc. |
| Fillers | Gives the skin a plump, full appearance | Maintains skin moisture and firmness, reduces skin hollows, and more |
| Botox | Temporarily weaken muscle movement | Reducing expression lines and sagging, etc. |
Since each treatment has a different approach and addresses different concerns, it’s important to choose the one that best suits the causes of your wrinkles and sagging skin.
Essential Information to Know Before Getting a Rejuran Injection
So far, we’ve covered frequently asked questions about Rejuran injections and the changes you can expect. Finally, we’ll provide a clear and easy-to-understand overview of the Rejuran injection treatment offered at Yayoi Clinic in Hiroshima, along with key points you should know. If you’re considering this treatment, we hope you’ll find this information helpful.
■Treatment Process: From Consultation to Aftercare
At Yayoi Clinic, we provide attentive, personalized care to each patient so that even first-time visitors can undergo treatment without anxiety.
The procedure for Rejuran injections is as follows:
- counseling
A doctor will examine your skin, andDetermine if Rejuran treatment is right for you。
We’ll carefully explain the treatment plan best suited to your concerns and skin type. - medical treatment (esp. surgical)
Before the procedure, the face is washed to ensure the skin is clean, and then the area is disinfected. After that, the doctor carefully injects Rejuran.
*To minimize discomfort during the procedure, we may use anesthetic patches or local anesthesia (additional fee applies). - End of Treatment · Aftercare
Once we confirm that the bleeding has stopped, the procedure is complete. We will provide you with instructions on how to care for yourself after the procedure and any precautions to take.
If you have any questions about aftercare, please feel free to contact us.
Please note that Rejuran injections cannot be administered to pregnant or breastfeeding women, or to individuals with pre-existing conditions such as allergic disorders or sarcoidosis.
■ How much pain can I expect, and how long is the recovery period?
Although individual experiences may vary, at Yayoi Clinic, we offer Rejuran injections with pain management options, including anesthesia upon request. Please feel free to consult with us if you have concerns about pain.
In addition, the general estimated downtime is,A few days to about a weekImmediately after the treatment, you may experience temporary redness or small, bumpy swellings, but these will subside naturally over time.One of the procedures that involves relatively little downtime and makes it easy to return to daily lifeIt is.
■Recommended Number of Sessions and Frequency for Noticing Results
Since Rejuran injections are a treatment that supports the skin's natural regeneration, first of all,Ideally, you should have the treatment 3 to 4 times in total, at a rate of once every 2 to 3 weeks.With repeated treatments, your skin’s foundation is strengthened, helping to maintain healthy skin. After that, we recommend regular maintenance treatments about once every six months to a year to help maintain these results.
▼Learn more about the Rejuran injection procedure
■Achieve Healthy Skin with Rejuran Injections
As we age, skin concerns such as fine lines, dark circles, and visible pores often become more noticeable, and it’s not uncommon for self-care alone to be insufficient to address them. Rejuran injections are a treatment option worth considering for such skin concerns. Before undergoing the procedure, be sure to confirm not only the expected changes and benefits but also the downtime and the recommended number of sessions. At Yayoi Clinic, we listen to your skin concerns and preferences to propose a treatment plan tailored to each individual. If you are considering Rejuran injections in Hiroshima, please feel free to contact us for a consultation.
Aesthetic Dermatology, Aesthetic Medicine, Aesthetic Surgery, Art Make-up Yayoi Clinic (YAYOI CLINIC) in Hiroshima introduces treatments for different problems of the skin, body, and face.
In order to offer you the best possible options, we assess each individual’s skin condition and develop a treatment plan tailored to your preferences, including the treatment duration, budget, and acceptable level of downtime.
If you have any concerns, please come for a counseling session first.
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Description of treatment] Rejuran
Recommended frequency of treatment: 3 to 4 times every 2 to 3 weeks / once every 6 months as maintenance.
Cost】¥58,000〜¥204,000 ※Prices vary depending on the area and number of times.
Side effects/risks] Pain, redness, swelling, internal bleeding
Equipment used.
Rejuran treatments include procedures using unapproved drugs or medical devices in Japan.
The medicines and medical devices used for treatment were imported from Japan under the judgment of our doctors. Please refer to the following for information on medicines and other items of concern for personal importation.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
Serious risks, side effects, etc. may not have been identified.
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.
