Dr. Takahiro Miki
Profile
After graduating from Kawasaki Medical University, he practiced orthopedic surgery at university hospitals and general hospitals, gaining experience in a wide range of fields, including trauma, sports injuries, regenerative medicine, and ultrasound-guided treatments. He continued to hone his skills as a board-certified orthopedic surgeon recognized by the Japanese Orthopaedic Association and joined YAYOI CLINIC in 2025. Specializing in skin-rejuvenation injections, Botox, and ultrasound-guided fascial release, he provides aesthetic medical treatments tailored to each individual’s needs, addressing both beauty and health.
If you’re interested in Botox injections at a cosmetic dermatology clinic in or around Naka Ward, Hiroshima City, you probably have many questions, such as “Is it painful? How effective is it?” or “Where can I find a skilled doctor with good reviews?” Botox injections are a treatment designed to reduce the appearance of expression lines and help you achieve a more defined facial contour. In this article, YAYOI CLINIC, a cosmetic dermatology clinic located in Naka Ward, Hiroshima City, explains the basics of Botox injections and answers some frequently asked questions.
What You Need to Know First! An Explanation of the Basics of Botox Injections

Before getting Botox injections at a cosmetic dermatology clinic in or around Naka Ward, Hiroshima City, let’s take a closer look at the basics of the procedure.
■What Results Can You Expect from Botox Injections? Treating Wrinkles, Jawline, and Excessive Sweating
Botox injections are a procedure that involves injecting a protein derived from Clostridium botulinum type A.It temporarily inhibits the release of neurotransmitters involved in muscle movement.. This helps relieve muscle tension and can address the following concerns.
| Effects | Specific Targets | Changes We Can Expect |
| Caring for Expression Lines | Horizontal wrinkles on the forehead, vertical wrinkles between the eyebrows, laugh lines at the corners of the eyes, and "prune-like" wrinkles on the chin, etc. | Relieves muscle tension and makes expression lines less noticeable |
| Care for Prominent Jawlines | Prominent Jaws Caused by Masseter Muscle Development | It relaxes muscle tension, creates a defined jawline, and helps alleviate teeth clenching. |
| Hyperhidrosis Care | Excessive sweating of the armpits, palms, and soles of the feet | It suppresses the activity of sweat glands and reduces excessive sweating. This helps reduce unpleasant odors. |
| Care for the Shoulders and Neck | Tension in the shoulders and neck, sloping shoulders, hunched shoulders, etc. | By targeting the trapezius muscle, we help create a sleek, streamlined look from the neck to the shoulders. |
■ Features of “Botox Vista®” and How It Differs from Other Formulations
Generally speaking, “Botox” refers to the registered trademark of a product manufactured and sold by Allergan, Inc. of the United States. Among these, Allergan’s “Botox Vista®” is widely used in Japan for wrinkle treatment and is a leading product with a significant global market share.Provided under strict quality controlBecause of this, it is the product of choice for those who prioritize safety and quality.
In addition, while South Korean products such as “Botulax” and “Neuronox” and the German product “Bocochua (Xeomin)” are widely known in Japan, the specific products used vary from clinic to clinic.
Below is a summary of the characteristics of the three Botox products offered at Yayoi Clinic, a cosmetic dermatology clinic in Naka Ward, Hiroshima City.
| Formulation name | feature |
| Botox Vista® | Quality control is a top priority, and with a proven track record worldwide, consistent results are being maintained. |
| NABOTA | A pharmaceutical product manufactured by Daeun Pharmaceutical in South Korea. It has been approved by the U.S. FDA (Food and Drug Administration) and is characterized by its high purity. |
| CORETOX | A product manufactured by Meditox of South Korea. It does not contain complex proteins, and precautions have been taken to minimize the risk of antibody production. |
If you prioritize a treatment with a proven track record worldwide, Botox Vista® is one option to consider; however, the most suitable product will vary depending on your budget and how often you plan to visit the clinic. It is important to thoroughly review the characteristics of each option during your consultation and make your choice only after you are fully satisfied with the information provided.
■ When Do the Effects Start? Estimated Duration by Body Part
Although the onset of Botox injections varies from person to person, the effects generally begin to appear gradually about 2 to 3 days after the procedure and stabilize in about 2 weeks. After that,A characteristic of this is that its effects gradually diminish over a period of 3 to 6 months.Please refer to the following guidelines for the duration of the effect.
| part | Approximate duration |
| Expression lines (forehead, between the eyebrows, outer corners of the eyes, etc.) | About 3 to 4 months |
| Large muscles such as the masseter (jaw muscle) | About 4 to 6 months |
| Treatment for Excessive Sweating (Underarms, etc.) | About 3 to 6 months |
If you wish to maintain your current condition, it is recommended that you receive regular treatments before your condition fully reverts to its original state. Generally speaking,In many cases, injections are continued every 3 to 4 months.That's probably true. However, if you undergo frequent treatments over a short period of time, your body may develop antibodies to Botox, which can reduce its effectiveness; therefore, it's important to maintain an appropriate interval between treatments as directed by your doctor.
What to Expect on the Day of Your Botox Treatment
Before getting Botox injections at a cosmetic dermatology clinic in the Naka Ward area of Hiroshima City, let’s take a closer look at the basics of the procedure. Here, we’ll walk you through the procedure at Yayoi Clinic.
■Step 1: Counseling and Medical Examination
First, the doctor will conduct a consultation after you have removed any makeup from the area where you wish to receive the injections. While discussing the look you’re hoping to achieve,We assess the condition of wrinkles and facial muscle movement to determine the appropriate injection sites and dosage.。
We’ll also explain the specific details of the procedure, the expected results, how long the effects will last, and any downtime involved, so please feel free to contact us if you have any concerns about pain or questions about the procedure.
■Step 2: Treatment
We will mark the appropriate injection sites for the Botox solution. If you are concerned about pain, we can apply an anesthetic cream beforehand. We will carefully inject the Botox solution into the target areas, such as the face, using an ultra-fine needle. The duration of the procedure varies from person to person depending on the specifics, butA short time—about 10 minutesIt is.
■Step 3: Aftercare and Postoperative Follow-Up
Starting on the day of your Botox injectionYou can apply makeup, wash your face, and take a bathThat's correct. However, please avoid rubbing or massaging the injection site for a few days. Also, on the day of the procedure, please refrain from strenuous exercise, saunas, and alcohol.
Please note that at Yayoi Clinic, we may ask you to return for a follow-up visit around 14 days after the procedure—when the effects are at their peak—and, following an examination, we may recommend an additional injection if necessary.
Frequently Asked Questions About Botox Injections

Finally, to help those considering Botox injections at cosmetic dermatology clinics in and around Naka Ward, Hiroshima City feel confident about undergoing the procedure, we’ve answered some frequently asked questions.
How much pain will I feel during the procedure?
The level of pain felt during Botox injections varies from person to person. Pain is felt when,A slight prick when the needle is inserted and when the medication is injected. Since the treatment time is short, the physical strain on your body should be relatively minimal.
Many clinics take steps to minimize the pain associated with Botox injections, such as using ultra-fine needles, applying numbing cream before the procedure, or cooling the treatment area.
■Can I feel the effects after just one injection?
Botox injections, in most cases,You can easily feel the difference after each treatment.This is a treatment. Muscle tension typically eases gradually over the course of a few days following the injection, and the muscles generally settle into a relaxed state within about 1 to 2 weeks.
■ Is there any downtime?
Botox injections are a procedure with minimal downtime. In rare cases, you may notice needle marks, swelling, redness, or bruising at the injection site, but these symptoms usually subside within a few days to a week. You can cover them with makeup and go about your daily routine as usual; however, if you have any concerns, please consult your doctor.
■ Conclusion.
If you are considering Botox injections at a cosmetic dermatology clinic in or around Naka Ward, Hiroshima City, be sure to understand the types of formulations, duration of effect, and downtime before your procedure. Choosing a doctor you can trust is the first step toward a treatment you’ll be satisfied with.
At Yayoi Clinic, a cosmetic dermatology practice in Naka Ward, Hiroshima City, we offer the Imaizumi Method® Botox injections. We tailor our treatments to each patient’s unique facial structure and facial muscle movements, aiming for a natural and beautiful result. Please feel free to schedule a consultation to discuss your options.
Aesthetic Dermatology, Aesthetic Medicine, Aesthetic Surgery, Art Make-up Yayoi Clinic (YAYOI CLINIC) in Hiroshima introduces treatments for different problems of the skin, body, and face.
In order to offer a better option for everyone, we will assess each person's skin condition and formulate a treatment plan that meets their needs in terms of treatment duration, budget, and acceptable downtime.
If you have any concerns, please come for a counseling session first.
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Description of procedure] Botox injection
Recommended frequency of treatment] Once every 3 to 4 months *Return around 14 days after the peak effect.
Cost】・1 unit ¥649~¥869 (+ ¥22,000 for treatment fee) ※There are individual differences depending on the formulation and number of units used.
Adverse effects/risks
Headache, pain and swelling at injection site, partial muscle weakness, redness, bruising, skin tightness, numbness, prickling sensation, nausea, temporary dent, internal bleeding, difficulty swallowing, pneumonia, anaphylaxis, severe lethargy, etc.
Equipment used.
Botox treatment includes treatments that are either unapproved drugs in Japan or treatments that are different from those approved for use in the pharmaceutical industry.
Drugs and medical devices used for treatment were imported through a private importation procedure based on the judgment of a physician at our clinic.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance, except for those approved by the pharmaceutical affairs bodies.
Information on safety, etc. in other countries
-BOTOX VISTA® approved by the Japanese regulatory authorities for the treatment of expression lines between the eyebrows or at the corners of the eyes in adults under 65 years of age.
-NABOTA receives U.S. FDA approval
-CORETOX® receives Korea MFDS approval
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.