Botox Injections

Addresses a wide range of concerns, including wrinkles, sagging skin, and hyperhidrosis

Botox injections are a procedure in which botulinum toxin type A (Botox) is injected to relax muscle tension and reduce excessive sweating and sebum secretion.

For those in Hiroshima City who are considering Botox injections,YAYOI CLINICWell thenWrinkles, Sagging, Prominent Jawline, Hyperhidrosis, Sebum ControlWe address a wide range of concerns, such as...We offer a variety of botulinum toxin products and recommend Botox injections using the product best suited to your concerns and preferences.

Reduces wrinkles caused by facial movements, such as those on the forehead, between the eyebrows, at the outer corners of the eyes, and on the chin

Non-Surgical Lifting for Sagging Jaws, Neck, and Jawline

We also address physical concerns such as stiffness in the shoulders and calves, and hyperhidrosis

Micro-Botox: Controls sebum, minimizes pores, reduces shine, and improves skin texture

Name of treatment	Elabotox
Treatment period frequency	Once every 3-4 months is the standard.
Treatment Time	About 10 minutes
Side Effects risk	Headache, pain and swelling at the injection site, partial muscle weakness, redness, numbness, bruising, prickling sensation, skin tightness, nausea, temporary indentation, and internal bleeding.
cost	40 credits 29,800 yen 60 credits 32,800 yen

Name of treatment	Elabotox
Treatment period frequency	Once every 3-4 months is the standard.
Treatment Time	About 10 minutes
Side Effects risk	Headache, pain and swelling at the injection site, partial muscle weakness, redness, numbness, bruising, prickling sensation, skin tightness, nausea, temporary indentation, and internal bleeding.
cost	59,600 yen (tax included) 40 units each side of Elabotox

Name of treatment	Erabotox + Botox Lift
Treatment period frequency	Once every 3-4 months is the standard.
Treatment Time	About 10 minutes
Side Effects risk	Headache, pain and swelling at the injection site, partial muscle weakness, redness, numbness, bruising, prickling sensation, skin tightness, nausea, temporary indentation, and internal bleeding.
cost	67,600 yen (tax included) Botox Lift + 60 units of Elabotox

Name of treatment	Erabotox + Botox Lift
Treatment period frequency	Once every 3-4 months is the standard.
Treatment Time	About 10 minutes
Side Effects risk	Headache, pain and swelling at the injection site, partial muscle weakness, redness, numbness, bruising, prickling sensation, skin tightness, nausea, temporary indentation, and internal bleeding.
cost	67,600 yen (tax included) Botox Lift + 60 units of Elabotox

Name of treatment	Botox lift
Treatment period frequency	Once every 3-4 months is the standard.
Treatment Time	About 10 minutes
Side Effects risk	Headache, pain and swelling at the injection site, partial muscle weakness, redness, numbness, bruising, prickling sensation, skin tightness, nausea, temporary indentation, and internal bleeding.
cost	39,800 yen (tax included)

Name of treatment	bunny botox
Treatment period frequency	Once every 3-4 months is the standard.
Treatment Time	About 10 minutes
Side Effects risk	Headache, pain and swelling at the injection site, partial muscle weakness, redness, numbness, bruising, prickling sensation, skin tightness, nausea, temporary indentation, and internal bleeding.
cost	22,000 yen + 869 yen per unit (tax included)

Name of treatment	Targeted Cool (Botox)
Treatment period frequency	each time *Treatment intervals vary depending on the purpose.
Treatment Time	About 10 minutes
Side Effects risk	Temporary redness and swelling, hypercooling, hyperpigmentation, itching, increased irritability, blistering, and changes in skin sensation.
cost	New 22,000 yen Normal price 25,000 yen

Name of treatment	RF (Volnewmer) x Botox Lift
Treatment period frequency	RF (Volnewmer): once every 4-6 months Botox Lift: once every 3-4 months
Treatment Time	30 to 50 min.
Side Effects risk	RF (Volnewmer): skin dryness, redness, swelling, internal bleeding, burns, etc. Botox lift: headache, localized pain at the injection site, eyelid drooping (ptosis), facial pain, swelling around the injection site, partial muscle weakness, redness, bruising, skin tightness, numbness, prickling sensation, nausea, etc.
cost	RF (Volnewmer): Light: ¥55,000 Standard: ¥99,000 Premium: ¥138,000 Botox Lift: 40 units $34,800 Botox Lift + Neck 60 units $39,800

Name of treatment	RF (Volnewmer) x Botox Lift x Botox
Treatment period frequency	RF (Volnewmer): once every 4-6 months Botox Lift: once every 3-4 months
Treatment Time	30 to 50 min.
Side Effects risk	RF (Volnewmer): skin dryness, redness, swelling, internal bleeding, burns, etc. Botox lift: headache, localized pain at the injection site, eyelid drooping (ptosis), facial pain, swelling around the injection site, partial muscle weakness, redness, bruising, skin tightness, numbness, prickling sensation, nausea, etc.
cost	RF (Volnewmer): Light: ¥55,000 Standard: ¥99,000 Premium: ¥138,000 Botox Lift: 40 units $34,800 Botox Lift + Neck 60 units $39,800

Name of treatment	Botox for the eyebrows
Treatment period frequency	Once every 3-4 months is the standard.
Treatment Time	About 10 minutes
Side Effects risk	Headache, pain and swelling at the injection site, partial muscle weakness, redness, numbness, bruising, prickling sensation, skin tightness, nausea, temporary indentation, and internal bleeding.
cost	22,000 yen + 869 yen per unit 30,690 yen (tax included) 10 units between the eyebrows

Name of treatment	Shoulder Botox
Treatment period frequency	About once every six months
Treatment Time	About 10 minutes
Side Effects risk	Temporary muscle heaviness, pain, internal bleeding, swelling
cost	400 units ¥109,600 (tax included)

Name of treatment	shoulder shaving
Treatment period frequency	About once every six months
Treatment Time	About 10 minutes
Side Effects risk	Temporary muscle heaviness, pain, internal bleeding, swelling
cost	100 units ¥34,800 (tax included)

Name of treatment	Shoulder Botox
Treatment period frequency	About once every six months
Treatment Time	About 10 minutes
Side Effects risk	Temporary muscle heaviness, pain, internal bleeding, swelling
cost	200 units ¥54,800 (tax included)

Name of treatment	Shoulder Botox
Treatment period frequency	About once every six months
Treatment Time	About 10 minutes
Side Effects risk	Temporary muscle heaviness, pain, internal bleeding, swelling
cost	200 units ¥34,800 (tax included)

Name of treatment	Botox for the chin
Treatment period frequency	Once every 3-4 months is the standard.
Treatment Time	About 10 minutes
Side Effects risk	Headache, pain and swelling at the injection site, partial muscle weakness, redness, numbness, bruising, prickling sensation, skin tightness, nausea, temporary indentation, and internal bleeding.
cost	About 10 minutes

Name of treatment	Botox injection for forehead
Treatment period frequency	Once every 3-4 months is the standard.
Treatment Time	About 10 minutes
Side Effects risk	Headache, pain and swelling at the injection site, partial muscle weakness, redness, numbness, bruising, prickling sensation, skin tightness, nausea, temporary indentation, and internal bleeding.
cost	20,000 yen (including tax) + 869 yen per unit

The characteristics of botulinum toxin products vary depending on the type.

At YAYOI CLINIC, we offer treatments approved by the Ministry of Health, Labor and Welfare,BOTOX Vista®(Botox Vista), approved by the U.S. FDA (approved as Jeuveau®)NABOTA®(Nabota), approved by the South Korean Ministry of Food and Drug Safety (MFDS)CORETOX®We have implemented (CoreTox).

We will recommend the most appropriate formulation based on the treatment area, your body type, and your preferences.

The effects of Botox injections begin to appear 2 to 3 days after treatment, peak around 14 days later, and typically last for 4 to 6 months.It is.

At YAYOI CLINIC, a doctor will check your condition approximately 14 days after the procedure and, if necessary, consider additional treatments such as another injection.

Also, Botox injectionsBy continuing this treatment every 3 to 4 months, it will be easier to maintain your skin’s healthy condition and the results of the treatment.。

At YAYOI CLINIC, we have mastered the Botox injection techniques used at “Imaizumi Skin Clinic” and “BIANCA CLINIC”—both of which provide cosmetic medical services primarily in Tokyo—and now offer these treatments here in Hiroshima.
Dr. Ito, the director of our clinic, received one-on-one, direct training from Dr. Akiko Imaizumi, director of Imaizumi Skin Clinic, and mastered diagnostic skills and injection techniques based on anatomy. Furthermore, he has adopted BIANCA CLINIC’s unique method of adjusting medication formulations to minimize pain.
・Anatomy-based injection techniques, a cornerstone of the Imaizumi Method®
・BIANCA CLINIC’s proprietary “Pain-Free Botox” formula
By drawing on our individual knowledge and skills, we strive to achieve natural and beautiful results tailored to each person’s skeletal structure and muscle movements.

What Is the Imaizumi Method®?

The Imaizumi Method® is an original injection technique developed by Dr. Akiko Imaizumi, Director of Imaizumi Skin Clinic (part of the Seisenkai Medical Corporation), based on her advanced anatomical knowledge and extensive experience in injection treatments.
While taking into account the potential risks and side effects of Botox injections,We aim for a more natural and beautiful result, taking into account the golden ratio that enhances each individual’s facial features.

Director, Imaizumi Skin Clinic, Seisenkai Medical Corporation

Dr. Akiko Imaizumi

Board Certified Dermatologist, Japanese Dermatological Association
A physician recognized worldwide for his high level of technical expertise and extensive experience in hyaluronic acid and Botox injections. In addition to treating over 7,000 patients annually, he serves as a “Certified Injection Instructor” accredited by AbbVie LLC (formerly Allergan Japan) and Galderma, providing technical training to physicians both in Japan and abroad. He also serves as a faculty member of the International Society of Aesthetic Plastic Surgery (ISAPS).

*“Imaizumi Method®” is a registered trademark of Imaizumi Skin Clinic (Registration No. 6134638).

▶ Imaizumi Skin Clinic Official Website

「今泉式®」注入法を考案した医療法人青泉会今泉スキンクリニック院長の今泉明子医師

Chairperson, SMILE LAND BIANCA CLINIC Medical Corporation; Representative Director, Creation Lab; CEO, NEMU SINGAPORE PTE. LTD.

Dr. Kazuaki Hotta

I manage a major aesthetic medicine clinic with a staff of over 20, bringing together leading physicians from various fields, including cosmetic surgery, cosmetic dermatology, and cosmetic internal medicine. We are dedicated to beauty and health, providing aesthetic treatments that bring a smile to our patients” faces. We have developed our original ”BIANCA METHOD” not only for Botox injections but also for hyaluronic acid injections. Drawing on our extensive experience with numerous cases, we are dedicated to helping each individual achieve their own refined beauty while minimizing pain and reducing stress.

▶ BIANCA CLINIC Official Website

A doctor will assess the treatment area, muscle mass, and frequency of treatments, and recommend the medication best suited for each individual.
If you have any specific medication requests, please don't hesitate to let us know.

Drug name	Approval	feature
BOTOX Vista®	Drugs Approved by the Ministry of Health, Labor and Welfare	・Manufactured by AbbVie LLC (formerly Allergan Japan) in the United States ・The only Botox product approved by the Ministry of Health, Labor and Welfare in Japan (as of June 2026) ・A formulation with a long track record of use▷For those who value quality, track record, and peace of mind
NABOTA®	FDA-Approved Drugs	・Developed by Medytox (South Korea) ・Approval obtained from the Ministry of Food and Drug Safety (MFDS) of South Korea ・Takes into account the risk of antibody production by removing complex proteins ・Taking into account the risk of allergic reactions▷For those considering continuing the program or wanting to minimize allergy risks
CORETOX®	Products Approved by the South Korean MFDS	・Developed by Medytox (South Korea) ・Approval obtained from the Ministry of Food and Drug Safety (MFDS) of South Korea ・Takes into account the risk of antibody production by removing complex proteins ・Taking into account the risk of allergic reactions▷For those considering continuing the program or wanting to minimize allergy risks

Drug name	Approval	feature
BOTOX Vista®	Drugs Approved by the Ministry of Health, Labor and Welfare	・Manufactured by AbbVie LLC (formerly Allergan Japan) in the United States ・The only Botox product approved by the Ministry of Health, Labor and Welfare in Japan (as of June 2026) ・A formulation with a long track record of use▷For those who value quality, track record, and peace of mind
NABOTA®	FDA-Approved Drugs	・Developed by Medytox (South Korea) ・Approval obtained from the Ministry of Food and Drug Safety (MFDS) of South Korea ・Takes into account the risk of antibody production by removing complex proteins ・Taking into account the risk of allergic reactions▷For those considering continuing the program or wanting to minimize allergy risks
CORETOX®	Products Approved by the South Korean MFDS	・Developed by Medytox (South Korea) ・Approval obtained from the Ministry of Food and Drug Safety (MFDS) of South Korea ・Takes into account the risk of antibody production by removing complex proteins ・Taking into account the risk of allergic reactions▷For those considering continuing the program or wanting to minimize allergy risks

Time required for treatment	Approx. 10 minutes *Treatment time varies depending on the counseling and treatment.
Approximate number of treatments	Once every 3-4 months *We recommend returning to the clinic around 14 days after treatment, when the effects are at their peak.
Approximate duration of treatment	Estimated Treatment Duration: To maintain the effects, a follow-up injection is required once every 3 to 4 months.
Bathing and washing face	Possible from the day after the treatment
make	Possible from the day after the treatment
taboo	The following persons are not eligible for treatment -Pregnancy -If you are breastfeeding -When there is a systemic neurojunction disorder -In case of hypersensitivity to botulinum toxin products *Please ask your doctor for details.
precautions	The following persons should carefully consider the procedure before undergoing it:] -When there is a systemic muscle disease Amyotrophic lateral sclerosis (ALS), Lambert-Eaton syndrome, myasthenia gravis, etc. -If there is a possibility of pregnancy -If you have experienced allergy to botulinum treatment in the past -If you are taking any medications Antibiotics, muscle relaxants, tranquilizers, etc. -Asthma and other chronic respiratory diseases and glaucoma -If you are receiving botulinum treatment at another medical institution Please be sure to inform us of the disease to be treated, the date of administration and the dosage. Please ask your doctor for details. Women of childbearing potential should use contraception until after the second menstrual period following the last dose. Men should use contraception for at least 3 months after the last dose. Side Effects and Risks: Headache, pain or swelling at the injection site, localized muscle weakness, redness, bruising, tightness of the skin, numbness, tingling, nausea, temporary indentation, internal bleeding, difficulty swallowing, pneumonia, anaphylaxis, severe lethargy, etc. Equipment used ・Botox treatments involve the use of medications that are not approved in Japan or procedures that differ from their approved indications. ・The pharmaceuticals and medical devices used in our treatments have been imported through personal import procedures based on the judgment of our clinic’s physicians. https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html There are no other domestically approved drugs with the same ingredients or performance, except for those approved by the pharmaceutical affairs bodies. Information on safety, etc. in other countries —Botox Vista® has received domestic regulatory approval for “expression lines between the eyebrows or at the corners of the eyes in adults under 65 years of age” (Approval Information: 22100AMX00398000) —NABOTA Receives U.S. FDA Approval (Jeuveau / BLA 761069) -CORETOX® receives Korea MFDS approval About the Adverse Reactions Relief System for Drugs In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.

Botox Injections BOTOX

Do you have any of these problems?

Wrinkles and Expression Lines

Jawline / Slimming Face

Sagging Skin · Neck

Pores and Skin Texture

Sweat & Odor

Stiff Shoulders and Tight Legs

For these concerns, please contact us. We recommend Botox injections.

For Those Considering Botox Injections in Hiroshima

Pickup Case Introduction

Botox Injections

YAYOI CLINIC'sBotox Injections.Why Choose Us

Anatomy-Based Imaizumi Method® Injection Design

BIANCA’s Pain-Sensitive Approach to Medication Adjustment and Treatment Techniques

Selecting Medications Based on the Purpose

Suggestions Based on the Balance Between the Face and the Entire Body

A follow-up system designed with both the effectiveness and long-term results in mind

Developed by "Imaizumi-style®" and BIANCA CLINIC We offer “pain-free Botox.”

What Is the Imaizumi Method®?

BIANCA’s Proprietary “Pain-Free Botox” Formula

Botox Injection Sites

Recommended Menus by Concern

Botox for Expression Lines

Elabotox

Botox under the arm

Shoulder Botox

Microbotox

Botox for the Nostrils and Corners of the Mouth

Botox for the Sternocleidomastoid Muscle

Botox to fit

Guidelines for Botox Injection Units

Botox Effects and Estimated Duration

YAYOI CLINIC'sList of Botox Injection Products

List of Botox Products

Treatment Details

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For these concerns, please contact us.
We recommend Botox injections.

YAYOI CLINIC's
Botox Injections.
Why Choose Us

Developed by "Imaizumi-style®" and BIANCA CLINIC
We offer “pain-free Botox.”

YAYOI CLINIC's
List of Botox Injection Products