Since the skin is an area where signs of aging are easily visible, many people probably want to “keep their skin looking beautiful forever.” For those individuals, skin-nourishing injections are highly recommended. With ongoing treatment, you’ll likely notice improvements in firmness, hydration, and skin texture, and the relatively minimal downtime is another appealing feature. In this article, we’ll explain the formulations recommended for facial skin care, broken down by area. Compare the characteristics of each to find the skin-nourishing injection that best suits your goals.
For treating fine lines around the eyes, try “SuneCos” and “Rejuran”

For treating fine lines around the eyes, Snekos and Rejuran are formulations that are expected to be effective.Here are the details.
■Snechos
Main Ingredients: Non-crosslinked hyaluronic acid, 6 types of amino acids
Expected Benefits: Fine line care, dark circle treatment, sagging skin care
Features: Has a smooth, silky texture and provides a natural finish even when injected into areas with thin skin.
Recommended frequency: 3 to 4 sessions every 2 to 3 weeks. After that, maintenance treatment once every six months.

Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | 2-minute walk from Hatchobori Station
Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | Hatchobori...
https://yayoiclinic.jp/sunekos
Located just a 2-minute walk from Hatchobori Station in Hiroshima, we offer cosmetic dermatology, cosmetic internal medicine, cosmetic surgery, and permanent makeup. Trust us with our proprietary, pain-reducing hyaluronic acid treatments, Botox, thread lifts, and skin-nourishing injections. Embrace “slow aging” as a strength in your life. With our personalized skin care plans available at a flat rate and the advanced VISIA skin analysis system, we’ll work alongside you to help you achieve your ideal skin.
■Rejuran
Main Ingredient: Polynucleotide
Expected Benefits: Fine Line Care, Firmness, Hydration
Features: Enhances the skin’s natural functions and repairs it from the inside out, leaving it supple and elastic.
Recommended frequency: 3 to 4 sessions every 2 to 3 weeks. After that, maintenance treatment once every six months.

Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | 2-minute walk from Hatchobori Station
Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | Hatchobori...
https://yayoiclinic.jp/rejuran
Located just a 2-minute walk from Hatchobori Station in Hiroshima, we offer cosmetic dermatology, cosmetic internal medicine, cosmetic surgery, and permanent makeup. Trust us with our proprietary, pain-reducing hyaluronic acid treatments, Botox, thread lifts, and skin-nourishing injections. Embrace “slow aging” as a strength in your life. With our personalized skin care plans available at a flat rate and the advanced VISIA skin analysis system, we’ll work alongside you to help you achieve your ideal skin.
For neck wrinkles: “Profilio” and “SkinVibe (formerly Volite XC)”

For treating neck wrinkles, Profhilo and SkinVibe (formerly Volite XC) are expected to be effective.Yes, you can. Details are as follows.
■Profilo
Main Ingredients: Two types of non-crosslinked hyaluronic acid
Expected Benefits: Volume, Firmness, and Anti-Sagging Care
Features: Promotes the production of collagen and elastin and targets the skin’s foundation to help restore natural firmness and volume. Skin
Recommended frequency: Twice at one-month intervals for the first two sessions. Once every six months thereafter.

Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | 2-minute walk from Hatchobori Station
Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | Hatchobori...
https://yayoiclinic.jp/profhilo
Located just a 2-minute walk from Hatchobori Station in Hiroshima, we offer cosmetic dermatology, cosmetic internal medicine, cosmetic surgery, and permanent makeup. Trust us with our proprietary, pain-reducing hyaluronic acid treatments, Botox, thread lifts, and skin-nourishing injections. Embrace “slow aging” as a strength in your life. With our personalized skin care plans available at a flat rate and the advanced VISIA skin analysis system, we’ll work alongside you to help you achieve your ideal skin.
■SkinVibe (formerly Volite XC)
Main Ingredient: Cross-linked hyaluronic acid
Expected Benefits: Reduces redness, treats fine lines, and moisturizes
Features: Improves the skin's moisture retention and elasticity. Blends easily into the skin for a natural finish.
Recommended frequency: About once every six months to once a year

Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | 2-minute walk from Hatchobori Station
Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | Hatchobori...
https://yayoiclinic.jp/volitexc
Located just a 2-minute walk from Hatchobori Station in Hiroshima, we offer cosmetic dermatology, cosmetic internal medicine, cosmetic surgery, and permanent makeup. Trust us with our proprietary, pain-reducing hyaluronic acid treatments, Botox, thread lifts, and skin-nourishing injections. Embrace “slow aging” as a strength in your life. With our personalized skin care plans available at a flat rate and the advanced VISIA skin analysis system, we’ll work alongside you to help you achieve your ideal skin.
"Jubelook" for Pores and Acne Scars

Jubelook is effective for skin-rejuvenating injections designed to treat pores and acne scars.Here's the answer. For crater-type acne scars,In Combination with Substitution TherapyDoing so will likely make the dents less noticeable. Details are as follows.
Main Ingredients: Polylactic acid and non-crosslinked hyaluronic acid
Expected Benefits: Pore Care, Acne Scar Care, Firmness
Features: Promotes collagen production. Improves skin elasticity and helps treat pores and acne scars.
Recommended frequency: About 2 to 3 times a month

Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | 2-minute walk from Hatchobori Station
Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | Hatchobori...
https://yayoiclinic.jp/juvelook
Located just a 2-minute walk from Hatchobori Station in Hiroshima, we offer cosmetic dermatology, cosmetic internal medicine, cosmetic surgery, and permanent makeup. Trust us with our proprietary, pain-reducing hyaluronic acid treatments, Botox, thread lifts, and skin-nourishing injections. Embrace “slow aging” as a strength in your life. With our personalized skin care plans available at a flat rate and the advanced VISIA skin analysis system, we’ll work alongside you to help you achieve your ideal skin.
For redness and dryness across the entire face, try “Purual” and “Bolite”

The skin-nourishing injections designed to treat redness and dryness across the entire face are Plural and Volite.Here are the details.
■Purreal
Main Ingredients: Polynucleotide (PN) derived from salmon DNA, mannitol, non-crosslinked hyaluronic acid
Expected Benefits: Redness Relief, Firmness, Hydration
Features: Excellent moisture retention and promotion of collagen and elastin production. Strengthens the skin’s natural barrier and gives it a youthful appearance.
Recommended frequency: 3 to 4 times every two weeks.

Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | 2-minute walk from Hatchobori Station
Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | Hatchobori...
https://yayoiclinic.jp/pluryal
Located just a 2-minute walk from Hatchobori Station in Hiroshima, we offer cosmetic dermatology, cosmetic internal medicine, cosmetic surgery, and permanent makeup. Trust us with our proprietary, pain-reducing hyaluronic acid treatments, Botox, thread lifts, and skin-nourishing injections. Embrace “slow aging” as a strength in your life. With our personalized skin care plans available at a flat rate and the advanced VISIA skin analysis system, we’ll work alongside you to help you achieve your ideal skin.
■Bolite
Main Ingredient: Cross-linked hyaluronic acid
Expected Benefits: Reduces fine lines, soothes redness, and moisturizes
Features: Hyaluronic acid’s anti-inflammatory properties and high moisture-retaining capacity help soothe redness and dryness.
Recommended frequency: About once every six months to once a year

Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | 2-minute walk from Hatchobori Station
Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | Hatchobori...
https://yayoiclinic.jp/volitexc
Located just a 2-minute walk from Hatchobori Station in Hiroshima, we offer cosmetic dermatology, cosmetic internal medicine, cosmetic surgery, and permanent makeup. Trust us with our proprietary, pain-reducing hyaluronic acid treatments, Botox, thread lifts, and skin-nourishing injections. Embrace “slow aging” as a strength in your life. With our personalized skin care plans available at a flat rate and the advanced VISIA skin analysis system, we’ll work alongside you to help you achieve your ideal skin.
For a lack of radiance across the entire face, try “Hydro” and “Profilor”

For a lack of radiance across the entire face, “Hydro” is effective, as is “Profilor,” which we also introduced as a treatment for neck wrinkles.It is.
■Hydro
Main Ingredients: 3 types of non-crosslinked hyaluronic acid
Expected Benefits: Wrinkle Care, Moisturizing
Features: Enhances moisture retention, promotes collagen and elastin production, and leads to smooth, radiant skin.
Recommended frequency: 3 to 4 times every two weeks

Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | 2-minute walk from Hatchobori Station
Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | Hatchobori...
https://yayoiclinic.jp/hydro
Located just a 2-minute walk from Hatchobori Station in Hiroshima, we offer cosmetic dermatology, cosmetic internal medicine, cosmetic surgery, and permanent makeup. Trust us with our proprietary, pain-reducing hyaluronic acid treatments, Botox, thread lifts, and skin-nourishing injections. Embrace “slow aging” as a strength in your life. With our personalized skin care plans available at a flat rate and the advanced VISIA skin analysis system, we’ll work alongside you to help you achieve your ideal skin.
In addition, “Snecos” and “Pural” are medications with the same characteristics as Hydro. Snecos is effective for treating fine lines and dark circles, while Pural is effective for treating wrinkles and redness, soIt's best to choose the product that suits your skin's needs.I am sure you will.

Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | 2-minute walk from Hatchobori Station
Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | Hatchobori...
https://yayoiclinic.jp/sunekos
Located just a 2-minute walk from Hatchobori Station in Hiroshima, we offer cosmetic dermatology, cosmetic internal medicine, cosmetic surgery, and permanent makeup. Trust us with our proprietary, pain-reducing hyaluronic acid treatments, Botox, thread lifts, and skin-nourishing injections. Embrace “slow aging” as a strength in your life. With our personalized skin care plans available at a flat rate and the advanced VISIA skin analysis system, we’ll work alongside you to help you achieve your ideal skin.

Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | 2-minute walk from Hatchobori Station
Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | Hatchobori...
https://yayoiclinic.jp/pluryal
Located just a 2-minute walk from Hatchobori Station in Hiroshima, we offer cosmetic dermatology, cosmetic internal medicine, cosmetic surgery, and permanent makeup. Trust us with our proprietary, pain-reducing hyaluronic acid treatments, Botox, thread lifts, and skin-nourishing injections. Embrace “slow aging” as a strength in your life. With our personalized skin care plans available at a flat rate and the advanced VISIA skin analysis system, we’ll work alongside you to help you achieve your ideal skin.
In addition to these basic treatments, we recommend “Micro-Botox.” Botox injections use botulinum toxin, andReduces sweat and sebum production to help minimize the appearance of enlarged poresWe also offer this treatment. As your skin becomes firmer, you can expect an even more refined and smooth complexion.

Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | 2-minute walk from Hatchobori Station
Hiroshima · Cosmetic Dermatology · Cosmetic Internal Medicine · Cosmetic Surgery · Permanent Makeup | Yayoi Clinic | Hatchobori...
https://yayoiclinic.jp/microbotox
Located just a 2-minute walk from Hatchobori Station in Hiroshima, we offer cosmetic dermatology, cosmetic internal medicine, cosmetic surgery, and permanent makeup. Trust us with our proprietary, pain-reducing hyaluronic acid treatments, Botox, thread lifts, and skin-nourishing injections. Embrace “slow aging” as a strength in your life. With our personalized skin care plans available at a flat rate and the advanced VISIA skin analysis system, we’ll work alongside you to help you achieve your ideal skin.
List of Skin Care Injections at YAYOI CLINIC

Here is a list of the skin-nourishing injections we’ve introduced so far.
- For dry, dehydrated skin, try “SkinVibe (formerly Volite XC)”
- For redness, try "Pural"
- For fine lines and firmness care, try “Rejuran,” “Hydro,” and “Snecos.”
- "Jubelook" for Pores and Acne Scars
- For volume loss, try “Profilor”
For skin-nourishing injections, visit YAYOI CLINIC
Skin-nourishing injections are a cosmetic treatment that allows you to choose a formulation tailored to your individual skin concerns, such as dryness, fine lines, redness, enlarged pores, and acne scars. By selecting the formulation best suited to your specific concerns, you can expect a more effective treatment.
At Yayoi Clinic, we offer a variety of skin-rejuvenating injections, including Snekos, Rejuran, Plural, Jubeluck, and Profhilo. If you’re unsure which treatment is right for you, we’ll discuss your skin condition and goals during a consultation to help you choose the best option. If you’re considering skin improvement or anti-aging treatments, please feel free to contact us.
Aesthetic Dermatology, Cosmetic Medicine, Cosmetic Surgery, and Art Makeup in Hiroshima YAYOI CLINIC offers treatments for different problems of the skin, body, and face.
In order to offer a better option to our customers, we will assess the skin condition of each individual and formulate a treatment plan that meets their needs in terms of treatment duration, budget, and acceptable downtime.
If you have any concerns, please come for a counseling session first.