Kiko Kono, M.D.
Profile
Graduated from Kawasaki Medical School. Worked as a dermatologist for about 20 years at core hospitals. After many years of experience and achievements, he became a cosmetic dermatologist. His practice style is to examine the skin thoroughly and pursue what is happening where on the skin and approach the problem. Her specialties include customized treatment, laser treatment, Botox, and skin growth injections. In her private life, she is a mother of two children.
MESONA J is a device that transdermally introduces agents such as vitamin C and collagen to improve skin problems. There are different colors for the agents used, each with different characteristics. In this issue, we will introduce the effects of each agent, as well as active ingredients according to skin problems and recommended treatments in combination with Mesona J.
What is Mesona J? Duration and disadvantages.

MESONA J is a transdermal delivery device developed in Japan.Transdermal introduction of active ingredients using mesoporation, a unique penetration functionThe electroporation system is a new type of electroporation system. In addition to conventional electroporation, which uses special electrical stimulation to create gaps in the skin's cell membranes, the system also includes a roller rope that uses electrical repulsion and permeation forces for better results.
Drugs used in MESONA J include active ingredients such as vitamin C derivatives, tranexamic acid, and arbutin. At Yayoi Clinic, we combine drugs according to skin concerns,Choice of white, pink or yellowIt is.
The duration of the effect varies from person to person. In the beginningLet's continue the treatment about once a month for about 3-4 months.The use of drugs may cause side effects. In addition, there are cases where side effects may occur due to the use of drugs. If you are worried about the procedure, please consult with the clinic first.
Characteristics of each chemical color [MESONA WHITE

MESONA WHITE is recommended for those who wish to improve spots, dullness, and melasma.Expected to increase moistureBecause it can be done, it is likely to be the choice of those with dry skin.
Characteristics of each chemical color [MESONA PINK

Masona Pink is,Improvement of redness, acne, and whitening effectsWe use agents that can Therefore, it is recommended for those who suffer from recurring acne, red face, and atopic dermatitis. The drug color is natural and derived from vitamin B12.
Characteristics of each drug color [Masona Yellow

The drug color of Mesonai Erow is due to vitamin B2. In Mesonai Erow,Expected to improve skin elasticity, luster, whitening effect, and poresIt can be done. It is recommended for those who are concerned about acne and open pores, and for those who want to improve the skin texture itself.
Active ingredients by skin concern

MESONA J uses a variety of drugs to improve skin quality. Each drug used has its own effect, and at Yayoi Clinic, we useUse a combination of drugs according to skin concernsWe will do so. Basic agents will be proposed based on your ideal skin condition, such as whitening, luminosity, and moisturizing. The doctor will confirm your concerns and wishes while checking your skin condition, so please have a consultation first.
Is there a recommended combination of treatment with Mesona J?

MESONA J has procedures that can be taken together for even greater effectiveness. The synergistic effects of the active ingredients are not the only benefits that can be expected when undergoing the procedure together. It is also possible to expect a reduction in downtime and a calming effect on redness and tingling sensation, which should be considered when undergoing the procedure.
■[Peeling
Peeling is the use of a chemical agent toHow to soften the stratum corneum on the skin's surface, leading to clear, translucent skin. At Yayoi Clinic, three types of peeling agents, massage peel, Milano peel, and Manuka peel, are used to improve skin problems.
Dermapen
Dermapen is,Treatment to improve skin texture by inserting microscopic needles into the skin's surface and using the skin's natural resilience.It is. At Yayoi Clinic, we offer a method that is tailored to individual skin concerns, using a combination of drugs and adjusting needle depth and puncture speed according to the skin's needs.
CEREC V
Selleck V is,Irradiation treatment with mild light energy to improve spots, dullness, redness, etc.It is. Equipped with 9 types of filters with different wavelengths, irradiation can be tailored to each individual's skin condition.
■ 【Super HIFE】.
What is a hyphen?High-density heat energy is irradiated to the SMAS layer of the skin, aiming to lift up the skin from the inside.The heat is applied to the necessary layers of the skin. By applying heat only to the necessary layers, it is less likely to damage the surrounding tissue. The Super HIF introduced at Yayoi Clinic is also designed to be pain-free.
Q-switched ruby laser
Q-switched Ruby laser is,Treatment for pigmentation such as spots and frecklesThe treatment can be performed while protecting the normal skin. The treatment approaches the melanin pigment that causes pigmentation while protecting the normal skin. 2 modes can be switched to allow irradiation of shallow to deep layers of skin, allowing treatment to be tailored to individual concerns.
If you want to receive MESONA J, go to YAYOI CLINIC.
Aesthetic Dermatology, Cosmetic Medicine, Cosmetic Surgery, Art Makeup in Hiroshima YAYOI CLINIC offers treatments for different skin, body, and facial concerns.
In order to offer a better option to our customers, we will assess the skin condition of each individual and formulate a treatment plan that meets their needs in terms of treatment duration, budget, and acceptable downtime.
If you have any concerns, please come for a counseling session first.
[Description of treatment] Mesona J.
Approximate number of treatments] Once every 4 weeks (1 course: about 4 to 6 treatments) *Depends on the treatment.
Cost】 ¥21,780~ ¥32,780
Adverse effects/risks
Redness, heat, itching, swelling, and rashes may occur due to allergic reactions to the drugs used.
In rare cases, some patients may feel a tingling sensation during the treatment. Please let us know if this is the case.
There may be a taste sensation of iron in the mouth and a flash of light due to the procedure near the eyes, but this is not a problem.
Equipment used.
Treatment of Mesotherapy includes procedures using domestically unapproved drugs or medical devices.
The medicines and medical equipment used for treatment were purchased from SeleneMedical, Inc. under the judgment of our physicians. Please refer to the right column for information on drugs and other items of note for personal purchase. https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in Japan
The following certifications have been obtained
Safety standard JIS-T 0601-1 (IEC60601-1:2005)
Electromagnetic compatibility (EMC) IEC60601-1-2:ed3
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.
Description of treatment] Peeling
Approximate number of treatments
Massage peel: Once every 2-3 weeks (about 5 times)
Milan Repeal: once every 2-3 weeks (3-10 times)
Manuka peel: once every 2 to 4 weeks (about 6 to 10 times)
*Depends on the nature of the treatment.
Cost] ¥12,800 - ¥43,560
Adverse effects/risks
Massage peel
Subcutaneous bubbles may occur within an hour or so, and thin skin may peel off.
Scabs may form. In this case, please be careful not to peel off the skin forcibly.
Depending on the skin condition, redness and peeling may occur. Please follow the doctor's instructions, as he/she will prescribe an ointment or other medication as necessary.
Milan Repeal
Some tingling pain may be felt during treatment.
Skin may become temporarily red, but this will subside within a few hours at the earliest, and within a few days at the latest. Always consult a physician if prolonged redness, skin peeling, or scabbing occurs.
Skin is prone to dryness and peeling during the treatment period, so please keep the skin well moisturized.
. Skin turnover is activated and acne may temporarily worsen.
Manuka peel
Symptoms seen during and after the procedure
Irritation, edema, erythema, blistering, erosions, ulceration, scaling, crusting, abnormal coloration, persistent erythema or itching, transient exacerbation of acne or pilar enlargement, telangiectasia, milia, etc.
Rare post-treatment symptoms
Allergic contact dermatitis and contact urticaria due to scarring, infection, peeling agents, etc.
Equipment used.
The treatment of massage peels, milanuri peels, and manuka peels involves the use of domestically unapproved pharmaceuticals or medical devices.
The medicines and medical devices used for treatment were imported by private individuals based on the judgment of the doctors at our clinic. Please refer to the following for information on medicines and other items of concern for personal importation.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
Significant risks and side effects may not be evident.
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.
Description of treatment] Dermapen 4
Approximate number of treatments: Once every 2 to 4 weeks, or once every 6 to 8 weeks (1 course: 3 to 5 treatments)
*The treatment interval depends on the degree of bleeding.
Cost] 1 time ¥31,800~¥36,800
Adverse effects/risks
Redness and tingling may occur, but will generally subside within 1 to 2 days.
Symptoms such as peeling, internal bleeding, and swelling may appear for 7-10 days.
In rare cases, old keratin may peel off, but please be careful not to peel it off forcibly.
Equipment used.
Dermapen4 treatment involves the use of a domestically unapproved drug or medical device.
The drugs and medical equipment used for treatment were purchased from PRSS.Japan, Inc. under the judgment of our doctors.
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
The following certifications have been obtained
ISO 13485
CE Standard
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.
Description of Treatment] CEREC V
Approximate number of treatments: Every 2 to 4 weeks for a total of 3 to 10 treatments.
Cost] ¥21,780
Adverse effects/risks
Pain, skin damage, pigmentation, scarring, excessive edema, erythema/purpura
・It depends on the individual, but you may feel pain or heat as if you were lightly popped during the treatment.
After the procedure, a slight burning sensation may remain, but it is usually only a slight reddening of the skin and is usually painless. It will disappear within a few hours to a few days. In some cases, a cream or ointment will be prescribed, so please follow the doctor's instructions.
The spots and mole areas may appear slightly darker for 2 to 3 days after the procedure.
Equipment used.
Cellec V treatment includes procedures using unapproved drugs or medical devices in Japan.
The medicines and medical devices used for treatment were imported from Jeisy Medical Inc. under the judgment of our doctors. Please refer to the following for information on drugs and medical devices that should be imported by individuals.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
The following certifications have been obtained
CE (2018.10)
MFDS (2017.8)
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.
Description of treatment] Hyphenated
The number of treatments depends on the area to be treated, so please ask your doctor for details. Re-irradiation is possible if there is an interval of 6 months after treatment.
Cost] ¥68,600 - ¥98,000
Adverse effects/risks
Although it varies from person to person, irradiation is accompanied by pain.
In very rare cases, burns may occur in people with sensitive skin or depending on their physical condition. If symptoms should occur, please contact our clinic.
The irradiated area may become unevenly hardened, but it will blend in within 3 to 4 weeks.
Swelling, swelling, and redness may occur. Please refrain from strenuous sports, excessive alcohol consumption, and saunas while experiencing swelling and swelling. Also, please refrain from massages for a week and be careful of friction.
Dull aches and numbness like muscle pain may occur for about a month after irradiation, but will gradually subside.
Equipment used.
SuperHIFE treatments include procedures using domestically unapproved drugs or medical devices.
Drugs and medical equipment used for treatment have been purchased and processed under the judgment of the clinic's physicians.
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
Significant risks and side effects may not be evident.
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.
Description of Treatment] Q-switched ruby laser
The number of treatments may vary from person to person depending on the symptoms and the extent of the disease.
Cost】¥1,500〜¥98,000 ※Additional treatment fee may be charged.
[Side effects/risks] Redness, pain, scabbing, hyperpigmentation, spotting, recurrent hyperpigmentation, temporary inflammatory hyperpigmentation, redness, blistering, crusting, etc.
Equipment used.
Machinery and Equipment (31) Medical Cauterization Equipment
Highly controlled medical device Ruby laser (36189000)
Specified maintenance controlled medical device Installation controlled medical device
The Ruby Z1 Nexus
Medical device approval number: 30200BZX00022000