Dr. Yayoko Ito
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Graduated from Hiroshima University School of Medicine. After working in the Department of General Medicine, he studied under doctors at the forefront of cosmetic medicine. After acquiring knowledge and skills in aesthetics, he became the director of YAYOI CLINIC in 2023. Her specialties include Botox, hyaluronic acid injections, and customized sagging treatment. His motto is to provide natural and pain-free treatments with careful consultation.
If you’re wondering, “What are Rejuran injections?” or “I’m looking for a cosmetic dermatology clinic in Hiroshima that offers Rejuran treatments,” this is a must-read. Rejuran (polynucleotide) injections are a cosmetic procedure gaining attention in South Korea as a form of skin rejuvenation therapy. In this article, we’ll explain in detail the characteristics of Rejuran injections, the skin changes you can expect, and how they differ from hydrafacials. We’ll also walk you through the process of receiving the treatment at Hiroshima YAYOI CLINIC. If you’re considering this treatment, please use this as a reference.
Questions About Rejuran Injections
Many people considering Rejuran injections have various questions, such as, “How effective is the treatment, and how long do the results last?” and “How does it differ from hydrafacials?” To start, here are some frequently asked questions for those considering treatment in Hiroshima.
■Q. What changes can I expect after the treatment, and how long do they last?
A. Rejuran injections are a treatment that acts on skin cells. Therefore, rather than noticing a change immediately after the procedure, you will gradually notice improvements in your skin’s firmness, elasticity, and hydration over the course of several weeks.
Rejuran injections are,Generally, treatments are performed several times (about 3 to 4 times) at intervals of a few weeks to a few months, and regular maintenance treatments are then recommended to maintain the skin’s condition.It is a treatment that is carried out over time.
Rather than a treatment that promises immediate results, this is best suited for those who want to achieve plump, smooth skin from a long-term perspective.
■ Q. How does this differ from other skin rejuvenation treatments (such as hydrafacials)?
A. Treatments often compared to Rejuran injections include HydraFacial, Jubelook, and Snekos. Here, we’ll focus on the differences between Rejuran and HydraFacial, which is most frequently compared to it.
| Rejuran Injections | injection of water into the eye of a patient | |
| Treatment Method | Handmade
(Some are machine-printed) |
Machine-printed |
| Objective. | Balances the skin's environment and supports healthy skin | Aiming to improve moisture and radiance |
| feature | ・Can be injected in small amounts into the desired areas
・Changes gradually become apparent |
・Delivers the medication evenly across the entire skin surface
・You're likely to notice a difference right after the treatment |
| skin problems | ・Concerned about a lack of firmness
・Fine lines are easily noticeable ・I'm concerned about the uneven texture caused by acne scars |
・Prone to drying out
・I'm concerned about my dull complexion ・I want to add some shine |
Rejuran injections are,The standard method involves a doctor using a syringe to inject the medication directly.On the other hand, the HydraFacial is a treatment method that uses specialized equipment to deliver the solution evenly. While Rejuran injections are often administered in small, precise doses to specific areas of concern, the HydraFacial is characterized by its ability to deliver the solution evenly across the entire skin surface.
■ Q. When can I start wearing makeup after the treatment?
A. It is best to avoid applying makeup immediately after a Rejuran injection. Generally speaking,Although it is said to be possible 24 hours later, care should be taken to avoid rubbing the skin too hard.It is.
In addition, since your skin is in a delicate state immediately after the treatment, it is important to avoid using harsh cleansers or cosmetics and to care for your skin gently. Furthermore, your skin becomes more susceptible to the effects of UV rays, so it is a good idea to take precautions against UV exposure, such as using a parasol or wearing a hat, when going outside.
What Exactly Are Rejuran Injections? An Explanation of Why They’re Gaining Attention and Their Key Features
Rejuran injections, currently trending in South Korea, are a treatment gaining attention from people concerned about issues such as loss of skin firmness and uneven skin texture. Here, we’ll explain in detail the characteristics of Rejuran injections, why they’re so popular, and what to expect in terms of pain and downtime.
■ "Polynucleotides (PN)" derived from salmon support healthy skin
A Rejuran injection is a treatment in which a substance containing polynucleotides (PN) extracted from salmon DNA is injected directly into the skin. By injecting it subcutaneously,Works on the fibroblasts in the dermis to support skin firmness, elasticity, and hydrationI will do so.
Generally, it is injected into areas of concern such as fine lines around the eyes, cheeks, and forehead, but it is also widely used on areas such as the neck and the backs of the hands.
■Why It’s Gaining Attention From People Struggling with Loss of Skin Firmness and Acne Scars
Rejuran injections are a popular treatment option for people concerned about loss of skin firmness, uneven skin texture, or skin irregularities caused by acne scars.
The main ingredient, polynucleotide (PN), is an ingredient expected to help improve skin condition.When injected into the dermis, it supports the production of hyaluronic acid, collagen, and elastinIt helps create the appearance of supple, elastic skin. It is also used by people concerned about uneven skin texture caused by acne scars, and is sometimes considered as a treatment aimed at achieving smooth, even-textured skin.
■How much pain can I expect, and how long is the recovery period?
With Rejuran injections, when inserting the fine needle,I sometimes feel a sharp, stabbing painThat's right. Also, in rare cases, you may experience a pressing sensation or a stinging feeling—which is characteristic of Rejuran—during the injection.
After the procedure, the injection site may appear temporarily swollen, but in most casesIt usually subsides within a few hours to a day.. In addition, you may experience mild redness, swelling, needle marks, or bruising, but these should fade within 2 to 3 days.
If your symptoms persist, it’s best to consult a doctor as soon as possible for peace of mind.
▼Learn more about the downtime associated with Rejuran injections
A 4-Step Guide to the Procedure on the Day of Your Rejuran Injection
Below, we’ll outline the process for receiving Rejuran injections at Hiroshima Yayoi Clinic, broken down into four steps.
■Step 1: Schedule a free consultation online or by phone
First, please schedule a free consultation using our online reservation form or by phone. At Hiroshima Yayoi Clinic, we place great importance on providing personalized consultations that address each client’s individual concerns, so even those new to cosmetic medicine can feel at ease discussing their needs with us. Please feel free to share your current concerns and wishes with us, such as “I’m concerned about loss of skin firmness or fine lines” or “I want to make my acne scars less noticeable.” You can choose an appointment date and time that fits your schedule, so we’ve created an environment that’s easy to visit even for those with busy lives.
▼Yayoi Clinic Appointment Website
▼ Yayoi Clinic LINE Appointment and Consultation Form
■Step 2: Medical Examination and Consultation with a Doctor
After you arrive at the clinic, a doctor will conduct an examination and consultation. We will thoroughly assess your skin condition and concerns, andAfter determining whether Rejuran injections are appropriate, we will propose a treatment plan tailored to each individual.Proposal: We’ll start by carefully explaining the underlying causes—such as “why this concern has arisen”—and then provide detailed information about the treatment, the expected results, downtime, and risks.
“Is the procedure painful?” “Are there other skin-rejuvenating injections besides Rejuran?”—even minor questions like these are welcome. At Hiroshima Yayoi Clinic, we carefully address every question, no matter how small, and help you feel at ease so you can make an informed decision about your treatment.
■Step 3: The procedure begins after anesthesia is administered
Before the procedure, we cleanse and wash the face to ensure the injection site is clean. For those who are sensitive to pain, we use anesthetic patches or local anesthesia. We begin the procedure only after confirming that the anesthesia has taken full effect.
Since Rejuran injections involve carefully administering the solution using an ultra-fine needle, the procedure time varies depending on the treatment area, butAbout 30 minutesAt Hiroshima Yayoi Clinic, we offer Rejuran injections—a pain-minimizing treatment developed exclusively by doctors at BIANCA CLINIC. If you have any concerns about skin rejuvenation injections, please feel free to consult with us first.
■Step 4: Explanation of Post-Treatment Aftercare and Precautions
After the procedure, the doctor will check that bleeding has stopped, explain the aftercare instructions and precautions, and the session will be complete. Immediately after the injection, you may experience slight swelling or redness, but these symptoms usually subside within a few days.
Also,After the procedure, be careful not to rub or massage the injection site too vigorously.That's right. Be sure to take thorough precautions against UV rays and follow your doctor's instructions for your skincare routine.
At Hiroshima Yayoi Clinic, we place great emphasis on post-treatment follow-up care. If you have any concerns or questions, please feel free to contact us.
▼Learn more about the Rejuran injection procedure
■If you're looking to achieve your ideal skin with Rejuran injections, visit Hiroshima Yayoi Clinic
In this article, we’ve introduced the characteristics of Rejuran injections, the changes you can expect, and the procedure process. Rejuran injections are best suited for those who, rather than seeking immediate results, wish to achieve their desired skin condition over the long term while supporting the skin’s natural health.
At Hiroshima Yayoi Clinic, we offer not only Rejuran injections but also a variety of other skin-rejuvenating injections, such as Snekos and Jubelook, allowing us to recommend treatments tailored to your specific concerns and ideal skin condition. If you’re interested in receiving Rejuran injections in Hiroshima or would like to learn more about skin-rejuvenating treatments, please feel free to contact Hiroshima Yayoi Clinic for a consultation.
Aesthetic Dermatology, Aesthetic Medicine, Aesthetic Surgery, Art Make-up Yayoi Clinic (YAYOI CLINIC) in Hiroshima introduces treatments for different problems of the skin, body, and face.
In order to offer a better option for everyone, we will assess each person's skin condition and formulate a treatment plan that meets their needs in terms of treatment duration, budget, and acceptable downtime.
If you have any concerns, please come for a counseling session first.
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Description of treatment] Rejuran
Recommended frequency of treatment: 3 to 4 times every 2 to 3 weeks / once every 6 months as maintenance.
Cost】¥58,000〜¥204,000 ※Prices vary depending on the area and number of times.
Side effects/risks] Pain, redness, swelling, internal bleeding
Equipment used.
Rejuran treatments include procedures using unapproved drugs or medical devices in Japan.
The medicines and medical devices used for treatment were imported from Japan under the judgment of our doctors. Please refer to the following for information on medicines and other items of concern for personal importation.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
Serious risks, side effects, etc. may not have been identified.
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.
