Dr. Takahiro Miki
Profile
After graduating from Kawasaki Medical University, he practiced orthopedic surgery at university hospitals and general hospitals, gaining experience in a wide range of fields, including trauma, sports injuries, regenerative medicine, and ultrasound-guided treatments. He continued to hone his skills as a board-certified orthopedic surgeon recognized by the Japanese Orthopaedic Association and joined YAYOI CLINIC in 2025. Specializing in skin-rejuvenation injections, Botox, and ultrasound-guided fascial release, he provides aesthetic medical treatments tailored to each individual’s needs, addressing both beauty and health.
For those in Hiroshima interested in receiving Profhilo injections under the jaw, YAYOI CLINIC, a cosmetic dermatology clinic in Hiroshima, provides an overview of the procedure. We’ll cover how Profhilo works, the results you can expect, and how it differs from other treatments for sagging skin. We’ve also summarized the procedure process and downtime, so if you’d like to learn more about Profhilo, please read on.
[Hiroshima Profilo] Sculpting the Jawline! What Is the Next-Generation Injection Treatment Available in Hiroshima?
For those in Hiroshima who are interested in undergoing Profhilo treatment to address sagging skin under the jaw, Yayoi Clinic in Hiroshima explains the basics of the procedure.
■Why Profhilo Can Address Sagging and Firmness Under the Jaw
PROFHILO® is a formulation created by combining two types of sodium hyaluronate with different molecular sizes through a special heat treatment process. The reason PROFHILO® is effective in addressing sagging and loose skin under the chin is that,Because it is expected to promote the remodeling (reconstruction) of skin tissue,It is.
A key feature of Profhilo is that it supports the function of fat cells and fibroblasts through the injection of the formulation. By promoting the increased production of components such as elastin and collagen—which provide the skin with elasticity and firmness—it addresses skin concerns associated with aging, such as loss of firmness and fine lines.
The key point is that, rather than physically filling in indentations and wrinkles with a formulation to smooth the skin, this approach works to stimulate the skin’s natural ability to rebuild itself. This allows you to achieve a more naturally firm complexion.
■What is the difference between Profhilo and Hyfu/fat-dissolving injections?
In addition to Profhilo, treatments that address sagging under the chin include HIFU and fat-dissolving injections. We’ve summarized the differences in how each procedure works in the table below.
| Name of treatment | How It Works |
| Profhilo (PROFHILO®︎) | Uncrosslinked (i.e., not chemically bonded) high- and low-molecular-weight sodium hyaluronate spreads out and promotes the reconstruction of skin tissue. |
| HIFU | By delivering high-density thermal energy, it heats the SMAS fascia and fat layers deep within the skin to tighten them. |
| Fat-dissolving Injections (Lipolysis) | Inject a medication to promote the breakdown of fat cells |
While both treatments can address sagging skin, their mechanisms of action differ significantly.
Profhilo is a treatment designed to promote skin tissue regeneration; HIFU is intended to tighten the deep layers of the skin; and fat-dissolving injections are designed to reduce fat cells. It is important to choose the appropriate treatment based on the cause of sagging.
■ Features of Profilo and Expected Results
Since Profhilo uses heat treatment—rather than chemicals—to bond two types of sodium hyaluronate, it is characterized by its soft texture.Because even a small amount spreads naturally over the entire skin surface, the procedure can be performed using relatively few injection sites.That's the key point.
Below is a summary of the skin concerns that can be addressed with Profhilo.
- Lack of firmness and elasticity
- laugh lines
- Dullness
- Lack of Texture and Luster
- Wrinkles on the face and neck
- Wrinkles on the back of the hand
This treatment is also ideal for those who want to care for skin that’s starting to show signs of aging.
Before Undergoing Profhilo Treatment for the Jawline in Hiroshima | Features of Hiroshima Yayoi Clinic
Next, for those in Hiroshima who are interested in undergoing Profhilo treatment to tighten the area under the jaw, we’ll explain the procedure at Hiroshima Yayoi Clinic. Let’s take a look at the treatment process, downtime, and the recommended frequency of treatments.
■The Profhilo Treatment Process
The procedure for Profhilo treatments at Yayoi Clinic is as follows.
- STEP 1: Consultation
- STEP 2: Treatment
- STEP 3: Aftercare
First, during a consultation, we’ll discuss your concerns and your desired results. The doctor will conduct a thorough examination and propose a treatment plan tailored to each individual’s skin type, condition, and preferences.
How long does the treatment take?It takes about 15 to 30 minutes—a relatively short time.That's correct. While the procedure can be performed without anesthesia, if you're concerned about pain, we can use anesthetic cream or a vibrating pen, so please let us know during your consultation.
After the procedure, we’ll review the results and explain any post-treatment precautions. If this is your first time receiving a Profhilo treatment,Since the doctor has a suggestion regarding the timing of the second injection, please check the schedule.Let's do it.
■ Downtime and Risk of Side Effects
After a Profhilo injection, you may experience the following symptoms.
- Pain at the injection site
- swelling
- internal hemorrhage
- blush
- itch
The downtime associated with Profhilo tends to be relatively short, although it varies from person to person,Generally, symptoms subside within a few days to a week.。
In addition to the points mentioned above, there is a risk of inflammation or allergic reactions; therefore, if you have any concerns about your postoperative recovery, please consult your doctor or a medical facility.
■Recommended Number of Sessions and Frequency for Experiencing Results
After the first Profhilo injection,It is recommended to wait one month before undergoing the second treatment....is being done. After that,Aim to continue regular treatment about once every six months.. Please note that the number of treatment sessions varies depending on the condition of your skin. To avoid having too few or, conversely, too many Profhilo treatments, please follow your doctor’s instructions.
You may notice a difference in your skin as early as after the first Profhilo injection, but generally speaking,Gradual changes began to appear about one month after the second treatmentYou’ll start to see results. Some people may view the fact that the effects aren’t immediate as a drawback of Profhilo. Others may feel anxious, wondering, “When will I start seeing the effects of Profhilo?”
Profhilo is not a treatment where you should expect immediate results. You’ll need to monitor your skin’s condition over the course of about 3 to 6 months after the procedure to see the effects. Even if you don’t notice a difference right away, there’s no need to regret it by thinking, “I tried Profhilo, but it didn’t work,” or “Maybe it was a mistake…”
Profilor in Hiroshima! Hiroshima Yayoi Clinic Answers Your Questions About Under-Chin Sagging Treatment
Finally, Yayoi Clinic in Hiroshima answers some common questions from people in Hiroshima who are considering Profhilo treatment to reduce concerns about the area under their jaw.
■When can I start wearing makeup or taking a bath after the treatment?
As long as you avoid the areas where Profhilo is injected, makeup is generallyPossible from the day after the treatmentThat's correct. You may take a short, light bath or wash your face on the day of your treatment. However, please refrain from using the sauna or taking long baths on the day of your treatment.
■How painful is the Profhilo treatment?
As mentioned earlier, since Profilo can be administered at a relatively small number of injection sites,A procedure that helps minimize discomfort, even for those who are anxious about the pain of injectionsIt is.
We use tools such as the "Buru Buru Pen" and anesthetic cream to ensure your treatment is as pain-free as possible.
■ Are there any precautions to take with Profilo?
Here are two important points to keep in mind regarding Profilo.
- Downtime may occur
- You need to be careful about how you take care of yourself after the procedure.
After a Profhilo treatment,There is a risk of swelling or bruising.. At Yayoi Clinic in Hiroshima, we perform procedures with risk management in mind; however, if you have an event or other commitment within the next two weeks, it is advisable to consult with a doctor to determine whether the procedure can be performed.
Also, please refrain from heavy drinking or strenuous exercise on the day of the procedure. Please avoid beauty treatments and massages for two weeks after the procedure.
■ Conclusion.
For those in Hiroshima who are interested in undergoing Profhilo treatment to address concerns under the chin, we’ve provided basic information about the procedure at Hiroshima Yayoi Clinic. Profhilo is an injectable treatment that addresses a wide range of skin concerns across various age groups. If you’ve been gathering information by looking at Profhilo case photos and before-and-after images, or reading blog posts summarizing the downtime process, why not schedule a consultation?
Aesthetic Dermatology, Aesthetic Medicine, Aesthetic Surgery, Art Make-up Yayoi Clinic (YAYOI CLINIC) in Hiroshima introduces treatments for different problems of the skin, body, and face.
In order to offer a better option for everyone, we will assess each person's skin condition and formulate a treatment plan that meets their needs in terms of treatment duration, budget, and acceptable downtime.
If you have any concerns, please come for a counseling session first.
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[Description of treatment] Profilo
Approximate number of treatments
Initial: 2 times at 1 month intervals
After the second time: once every six months
*The number of treatments depends on the skin age.
Cost] ¥82,000 - ¥158,400 *Prices vary depending on the number of times.
Side effects/risks] Pain at the injection site, inflammation, redness, itching, swelling, internal bleeding, allergic reaction due to body constitution, etc.
Equipment used.
Profibro's treatment includes procedures using domestically unapproved drugs or medical devices.
The medicines and medical devices used for treatment were imported from Japan under the judgment of our doctors. Please refer to the following for information on medicines and other items of concern for personal importation.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
Serious risks and side effects may not be evident.
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.
