Kiko Kono, M.D.
Profile
Graduated from Kawasaki Medical School. Worked as a dermatologist for about 20 years at core hospitals. After many years of experience and achievements, he became a cosmetic dermatologist. His practice style is to examine the skin thoroughly and pursue what is happening where on the skin and approach the problem. Her specialties include customized treatment, laser treatment, Botox, and skin growth injections. In her private life, she is a mother of two children.
YAYOI CLINIC, a cosmetic dermatology clinic in Hiroshima, explains Target Cool. Target Cool is a new cooling treatment device that is attracting a lot of attention. Although it is a cosmetic medical device used in many countries, there are still not many clinics in Japan that have adopted it. YAYOI CLINIC, a cosmetic dermatology clinic in Hiroshima that offers Target Cool treatments, explains its features and how it works to deliver results. Please use this as an opportunity to deepen your understanding of Target Cool.
Essential Information to Know Before Taking the Target Cool Test in Hiroshima

Target Cool (TARGET COOL🄬) is attracting attention as a new aesthetic medical deviceCooling Therapy Treatment SystemThat's right. While there aren't many clinics in Japan that have adopted this technology yet, it is being used in 30 countries worldwide (as of December 2024), primarily in Europe and South Korea, which is known as a leader in the beauty industry.
Before undergoing Target Cool treatment in Hiroshima, let’s first take a look at how it works and its effects.
■How Target Cool Works and Its Expected Benefits
One of the key features of the Target Cool system is that,A Special Cooling Technology Using Carbon Dioxide. Using precision cooling technology, CO2 gas is sprayed at high speed while simultaneously cooling the material rapidly. This allows for,It is expected to significantly reduce treatment-related pain and the burden on the skinCan be done.
Another key feature is “ice needling technology,” which transforms cooled medication into microscopic ice crystals and delivers it into the skin.By instantly cooling the medication, it is expected to deliver the active ingredients deep into the skin while minimizing degradation of their properties.The following is a summary of the results of the project.
■Target Cool's 3 Modes
Target Cool features the following three modes:
・Boost Mode
Using ice-needling technology, we deliver formulations tailored to specific skin concerns—including Botox, tranexamic acid, Purial Silk, and Jubelook—into the skin. Because these ingredients are delivered to the skin while minimizing degradation,You can expect to see improvements in your skin relatively quicklyCan be done.
・Cooling Mode
The cooling mode, which allows for cooling and spraying while maintaining a temperature range of -10°C to -5°C, is used to treat acne-prone skin. By precisely adjusting the cooling time and temperature, this mode is expected to help reduce inflammation and soothe skin redness and acne.
・Freezing Mode
Freezing mode involves spraying CO2 at extremely low temperatures—as low as -79°C—to destroy diseased tissue, such as warts. Through rapid freezing,By repeatedly freezing the abnormal tissue, this process promotes skin regeneration.. Although it is not very common in Japan, it is used in dermatological treatments overseas.
Yayoi Clinic in Hiroshima Explains the Features of Target Cool

The differences between Target Cool and conventional treatments can be summarized as follows.
- A treatment process that delivers noticeable results in a short amount of time
- Designed with pain management in mind and minimal downtime
- Can address a variety of skin concerns
Yayoi Clinic, a cosmetic dermatology clinic in Hiroshima that offers Target Cool, explains its benefits in detail.
■A treatment process designed to deliver results in a short amount of time
Target Cool is a treatment that applies CO2 to the skin’s surface, with the aim of improving blood flow and metabolism. The process increases CO2 levels in the capillaries, making it easier for oxygen to be released into the tissues—a phenomenon known as the “Bohr effect.” ThisThe Bohr effect is expected to promote metabolism, support regeneration, and reduce inflammation.Can be done.
Also, at Target Cool,Allows the drug to be delivered to a shallower layer than with conventional injection treatmentsThat's why it's said to make it easier to feel the effects more quickly.
■Designed with pain and downtime in mind
Unlike traditional injection treatments such as skin-rejuvenating injections, Target Cool does not use needles. Furthermore, by cooling the skin,It slows down the electrical activity of nerve fibers, producing a temporary anesthetic effect.. As a result, it is characterized by minimal pain and bruising, as well as relatively little downtime. The use of ice-needling technology helps reduce the risk of injection marks and bruising. Therefore, it is recommended for those who were hesitant to try traditional skin booster treatments due to concerns about pain or downtime.
■ Suitable for a variety of skin concerns
Target Cool features three treatment modes: Boosting Mode, Cooling Mode, and Freezing Mode. This allows it to address not only skin texture improvement but also a wide range of skin concerns, such as acne, warts, and hemangiomas.
Here's an overview of the process at Target Cool's Hiroshima Yayoi Clinic
Here, we’ll walk you through the treatment process at Yayoi Clinic, which offers Target Cool.
■ Counseling
A doctor will examine your skin condition to determine whether the treatment is appropriate for you.
Since Target Cool may require careful consideration before treatment in some cases, the doctor will thoroughly discuss the following points with you during your consultation.
- Medical History (Yes/No)
- Medications Currently Being Taken
- Other Beauty Treatments to Combine With This One
- Pregnancy or Possible Pregnancy
- Specific Information Regarding Health Status
Treatment flow and time required
Depending on the clinic, Target Cool may offer only a limited selection of treatment modes. At Yayoi Clinic, you can choose the mode that best suits your needs. While this varies depending on the treatment area,The treatment typically takes about 30 minutes.The first two are the following.
■Downtime and Post-Treatment Care
Target Cool is a treatment that involves relatively little pain and downtime. However, in some cases, temporary redness, swelling, or itching may occur due to allergies to the medication or temperature changes.
Depending on the combination of treatments, you can apply makeup 3 to 4 hours after the procedure. You can also bathe and wash your face on the same day as the procedure.
For consultations regarding Target Cool, visit Yayoi Clinic in Hiroshima.

Yayoi Clinic, a cosmetic dermatology practice in Hiroshima that offers Target Cool treatments, has adopted a unique consultation system. During the initial consultation, we conduct a thorough examination and provide detailed explanations—starting with the mechanisms of aging and extending to the causes of skin concerns—to help you gain a fundamental understanding of cosmetic medicine. Our doctors carefully assess each patient’s skin condition and develop and propose appropriate treatment plans tailored to their preferences—including the desired pace of treatment, budget, and concerns regarding downtime and pain.
In addition to cosmetic procedures, we can also recommend doctor-formulated skincare products tailored to your specific skin concerns. At our skincare clinic, we provide advice on skincare routines suited to your skin type and recommend appropriate skincare products. Even if you’re still hesitant about cosmetic procedures, please feel free to consult with us.
■ Conclusion.
Target Cool is a cooling treatment technology designed to address a wide range of skin concerns, such as those looking to improve their skin texture or those worried about acne. Since the procedure involves relatively little downtime and pain, it’s a good option for people who have been hesitant about the pain associated with traditional laser or injection treatments. If you’re hesitant about traditional cosmetic procedures that involve pain or downtime, it’s a good idea to start by consulting with a clinic.
Aesthetic Dermatology, Aesthetic Medicine, Aesthetic Surgery, Art Make-up Yayoi Clinic (YAYOI CLINIC) in Hiroshima introduces treatments for different problems of the skin, body, and face.
In order to offer a better option for everyone, we will assess each person's skin condition and formulate a treatment plan that meets their needs in terms of treatment duration, budget, and acceptable downtime.
If you have any concerns, please come for a counseling session first.
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Description of treatment] Targeted Cool
The treatment interval depends on the purpose of the treatment.
Cost】¥22,000〜¥63,000 ※Fees vary depending on the number of times, etc.
[Side effects/risks] Temporary redness and swelling, hypercooling, hyperpigmentation, itching, increased sensitivity, blistering, and changes in skin sensation.
Equipment used.
TargetCool® treatments include procedures using domestically unapproved drugs or medical devices.
Drugs and medical devices used for treatment were imported through a private importation procedure based on the judgment of a physician at our clinic.
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
-FDA, CE, KFDA (MFDS) approval
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.